The enamel organic matrix: structure and function
نویسنده
چکیده
Correspondence to: Sérgio Roberto Peres Line Faculdade de Odontologia de Piracicaba UNICAMP Avenida Limeira, 901, Areião CEP: 13.414-903 Caixa Postal: 52 Piracicaba-SP, Brasil Phone:+55-19-3412-5333 E-mail: [email protected] Abstract Dental enamel is the most mineralized tissue in the vertebrate body and contains the largest known biologically formed hydroxyapatite crystals. Its formation occurs extracellularly through the collaboration of a proteic transient framework (the enamel organic matrix), which controls hydroxyapatite crystal growth, morphology and orientation. This matrix is deposited with a small amount of mineral during the secretory stage of amelogenesis. The organic components begin to be degraded in the transition stage and are extensively corrupted, and almost entirely replaced by the inorganic crystallites during maturation stage. The present paper reviews current knowledge on the structural biology of the enamel organic matrix.
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